中间图

Or

雷哥网GMAT>题库>精选题库>阅读RC>16080

阅读RC-16080 (第3/3题) Time Cost00:00
收藏
报告题目错误
请选择错误类型:
请描述一下这个错误:

取消

Caffeine, the stimulant in coffee, has been called "the most widely used psychoactive substance on Earth. "Snyder, Daly, and Bruns have recently proposed that caffeine affects brain of by countering the activity in the human brain of a naturally occurring chemical called adenosine. Adenosine normally depresses neuron firing in many areas of the brain. It apparently does this by inhibiting the release of neurotransmitters, chemicals that carry nerve impulses from one neuron to the next.

Like many other agents that affect neuron firing, adenosine must first bind to specific receptors on neuronal membranes. There are at least two classes of these receptors, which have been designated A1 and A2. Snyder et a1. propose that caffeine, which is structurally similar to adenosine, is able to bind to both types of receptors, which prevents adenosine from attaching there and allows the neurons to fire more readily than they otherwise would.

For many years, caffeine's effects have been attributed to its inhibition of the production of phosphodiesterase, an enzyme that breaks down the chemical called cyclic AMR. A number of neurotransmitters exert their effects by first increasing cyclic AM P concentrations in target neurons. Therefore, prolonged periods at the elevated concentrations, as might be brought about by a phosphodiesterase inhibitor, could lead to a greater amount of neuron firing and, consequently, to behavioral stimulation. But Snyder et aI point out that the caffeine concentrations needed to inhibit the production of phosphodiesterase in the brain are much higher than those that produce stimulation. Moreover, other compounds that block phosphodiesterase's activity are not stimulants.

To buttress their case that caffeine acts instead by preventing adenosine binding, Snyder et al compared the stimulatory effects of a series of caffeine derivatives with their ability to dislodge adenosine from its receptors in the brains of mice. "In general,"they reported "the ability of the compounds to compete at the receptors correlates with their ability to stimulate locomotion in the mouse i. e., the higher their capacity to bind at the receptors, the higher their ability to stimulate locomotion." Theophylline, a close structural relative of the most effective compounds in both regards.

There were some apparent exceptions to the general correlation observed between adenosine-receptor binding and stimulation. One of these was a compound called 3-isobutyl-1-methylxanthine (IBMX), which bound very well but actually depressed mouse locomotion. Snyder et al suggest that this is not a major stumbling block to their hypothesis. The problem is that the compound has mixed effects in the brain, a not unusual occurrence with psychoactive drugs. Even Caffeine, which is generally known only for its stimulatory effects, displays this property, depressing mouse locomotion at very low concentrations and stimulating it at higher ones.

The author quotes Snyder et al. in highlight text most probably in order to




  • 分析A选项
    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
  • 分析B选项
    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
  • 分析C选项
    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
  • 分析D选项
    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
  • 分析E选项
    xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

音频解析

00:00/00:00

300雷豆
暂无雷哥网文字解析
当前还没有完善解析,欢迎在这里提交你的解答,等待老师审核~

题目讨论 (3条评论)

用户头像
提交
  • 用户头像
    TinaT

    题目分析:引号in order to题。答案要在引号中的总结句去找,答案就是总结句的改写。大家记得文章中我重点划出的in general吗?因此看完每个选项的第一个单词就可以选出答案B:summarize,只有这个单词是in general的改写。
    当然,严谨起见,我们来每个选项看一下:
    (A) reveal some of the assumptions underlying their theory  第三段说的是实验,没有提假设,错
    (B) summarize a major finding of their experiments 总结、主要、发现、实验――多么完美的改写啊。
    (C) point out that their experiments were limited to the mouse 没有说过,错
    (D) indicate that their experiments resulted only in general correlations 大家要注意这种极端词。文章中如果没有出现过,答案中出现了,一般必然是错的。
    (E) refute the objections made by supporters of the older theory 这是第二段的内容。引号出现在第三段,根据文字对应法,答案不可能在第二段。
    1 0 回复 2018-10-04 17:25:56
  • 用户头像
    liao8520

    没有 objections
    In general--summarize
    0 0 回复 2018-08-27 10:16:50
  • 用户头像
    Lauriere

    没有highlight
    0 0 回复 2018-06-25 11:05:14
    题号选择

    科目: 阅读RC

    • 句子改错SC
    • 逻辑CR
    • 阅读RC
    • 数据充分DS
    • 问题求解PS
    • 综合推理IR

    来源: 精选题库

    • 全部
    • OG20
    • OG20新题
    • OG19新题
    • OG18新题
    • OG18分册
    • OG17新题
    • OG16
    • OG12
    • 破解版12
    • 破解版08
    • 破解版07
    • GWD
    • 精选题库
    • OG18自测章
    • Manhattan
    • magoosh
    • 难题300
    本题信息

    2m17s

    平均耗时

    56.6%

    平均正确率

    • 题目来源1:精选题库

    该题由网友csyH4ZV提供 上传GMAT题

    • 手机注册
    • 邮箱注册
    登录>







    关闭图标

    标题图

    • 图标

      知识库学习

      GMAT语法、逻辑、阅读、数学各单项备考知识点学习及测验
    • 图标

      在线做题

      包含GMAT各单项必考知识点题目、OG/PREP/GWD/雷哥讲义题目、难度650/680/700/730题库题目练习及题目解析
    • 图标

      在线模考

      语文套题/数学套题/全套仿真模考,包含GWD/PERP/精选模考等上百套套题模考
    • 图标

      在线测评

      适合5种不同基础的GMAT学员,测评后可自动出具分数报告及复习计划指导
    • 图标

      资料下载

      GMAT必备备考资料下载、鸡精下载、课程课件等免费下载
    • 图标

      课程学习

      注册会员后,可在GMAT课程区,选择免费直播课程及公开课程进行在线学习
    ×
    请你选择你要查看的模考成绩单
    立即开通 暂不开通
    加载图片
    网络异常